Crystal engineering of exemestane to obtain a co-crystal with enhanced urease inhibition activity
نویسندگان
چکیده
منابع مشابه
Crystal Engineering Studies: polymorphs and co-crystals
We review the key topics of one of the areas with the biggest impact of the last years in the chemical and pharmaceutical industry that is Crystal Engineering. The relevance of polymorphs and co-crystals from different points of view is been highlighted and broadly illustrated by means of several recent examples of studies carried out in this field. In addition, the most suitable instrumental t...
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A target of best dissolution improvement of poorly soluble drugs is a necessity for the success of formulation in industry. The present work describes the preparation, optimization, and evaluation of a new spherical agglomeration technique for glimepiride as a model of poorly soluble drugs. It involved the emulsification of a drug solution containing a dispersed carrier that tailors the crystal...
متن کاملA New Crystal Engineering Technique for Dissolution Enhancement of Poorly Soluble Drugs Combining Quasi-emulsion and Crystallo-co Agglomeration Methods
A target of best dissolution improvement of poorly soluble drugs is a necessity for the success of formulation in industry. The present work describes the preparation, optimization, and evaluation of a new spherical agglomeration technique for glimepiride as a model of poorly soluble drugs. It involved the emulsification of a drug solution containing a dispersed carrier that tailors the crystal...
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normal 0 false false false en-us x-none ar-sa dear editor i read with interest the study conducted by karrari and colleagues regarding “iranian crystal a misunderstanding of the crystal-meth” published in your journal. [ 1 ] in this study, the authors have explained that the pattern of substances of abuse is varied in different parts of the world , also in iran, and the main ingredient of stree...
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A number of hydrogen-bonded co-crystals, consisting of a cinnamic acid derivative and a pyridyl co-crystallizer, have been synthesized and their properties investigated by X-ray diffraction. Samples were prepared by recrystallization or solvent drop grinding of trans-cinnamic acid (1), 4-methylcinnamic acid (2), 4-methoxy cinnamic acid (3) or 3,4-methoxy cinnamic acid (4), with 4,4-dipyridyl (A...
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ژورنال
عنوان ژورنال: IUCrJ
سال: 2020
ISSN: 2052-2525
DOI: 10.1107/s2052252519016142